UIS and Santo Tomás University develop new patent to control the Aedes Aegypti mosquito

With the intention of stopping the spread of the Aedes aegypti mosquito, the agent that transmits diseases such as Dengue, Chikungunya and Zika, members of the School of Chemistry of the Industrial University of Santander, hand in hand with researchers from the Santo Tomás University , developed a new process for the preparation of 2- (arylamino) acetonitrile derivatives, substances with larvicidal properties that control the growth of the population of this insect.

The diseases of which the Aedes aegypti mosquito serves as the main vector of spread mainly affect the inhabitants of tropical areas, such as Colombia. Recently, the alarms against diseases such as Dengue have been activated after more than 71,000 cases have been reported so far in 2020. In the American continent last year there was an outbreak of more than three million cases, reaching its historical maximum. According to figures from the WHO, in the world 500,000 people are hospitalized with serious affectations due to this disease.

“At present there are chemical agents for the control of mosquitoes, such as chlorinated hydrocarbons, organophosphates, carbamates and pyrethroids, many of them have induced resistance in mosquito populations” says Vladimir V. Kouznetsov, professor at the School of Chemistry and director of the Biomolecular Organic Chemistry Laboratory (LQOBio), who mentions that the excessive use of these has generated a negative environmental impact.

With this new patent insecticides were developed that break the cycle of metamorphosis of the mosquito in its larval stage, contributing to achieve a successful selective chemical control that favors the population exposed to the diseases produced by this insect.

“Obtaining a patent is not the final goal of our research work on this subject, it is a logical step from our fundamental studies to practical applications. The patented results drive and motivate us to continue our work in search of new achievements, challenges and research that lead to contributions for the benefit of the community ”, says Professor Kouznetsov, who together with UIS students, Elkin Flórez and Carlos Puerto , and Professor Leonor Vargas and her student Pedro Sanabria attached to the Environmental Research Group for Sustainable Development (GIADS) of the Santo Tomás University, developed the work that led to the obtaining of a new national patent for the two universities, delivered by the Superintendency of Industry and Commerce – SIC.

The work does not end with this achievement, now the same human team will continue its research to formulate an insecticide that is safe for people and the environment.

Vladimir V. Kouznetsov, professor at the UIS School of Chemistry.

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